Best en bloc for 35 mm depressed rectal LST?

A) Cold snare

B) Avulsion

C) ESD

D) Piecemeal

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The answer is

C) ESD

A 35 mm depressed LST carries a significant risk of submucosal invasion. Endoscopic submucosal dissection (ESD) is the only technique that reliably achieves en bloc resection for lesions >20 mm with depressed morphology, allowing accurate pathological staging.

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